Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RCIX2365mRNA cleavage/polyadenylation specificity factor,100 kD subunit. (636 aa)    
Predicted Functional Partners:
psmB
20S proteasome, beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
   
 0.942
rpl26e
50S ribosomal protein L26E; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
  
 
 
 0.883
rpoE
DNA-directed RNA polymerase, subunit E.
  
 
   0.831
rpoB2
DNA-directed RNA polymerase, subunit B2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.802
rpoA1
DNA-directed RNA polymerase, subunit A1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.802
rpoE2
Putative DNA-directed RNA polymerase, subunit E2; Stimulates transcription elongation; Belongs to the archaeal Spt4 family.
  
 
 
 0.801
rpoD
DNA-directed RNA polymerase, subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 
 0.782
rpoA2
DNA-directed RNA polymerase, subunit A2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
   0.754
rpoB1
DNA-directed RNA polymerase, subunit B1; Belongs to the RNA polymerase beta chain family.
    
   0.732
rpoL
DNA-directed RNA polymerase, subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
    
 
 0.728
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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