Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RCIX2387Hydrogenase, membrane subunit 4-like protein (HycC-like). (681 aa)    
Predicted Functional Partners:
RCIX2386
Hydrogenase, membrane subunit 3-like protein (EchB-like).
 
 
 0.990
RCIX2383
Hydrogenase, large subunit-like protein (HycE-like).
 
 
 0.987
RCIX2382
Hydrogenase, small subunit-like protein (HycG-like).
 
 
 0.978
RCIX2385
Hydrogenase, membrane subunit 2-like protein.
 
  
 0.969
echC
Ech hydrogenase, subunit C.
  
 
 0.903
echA
Ech hydrogenase, subunit A.
 
 
0.897
RCIX557
Predicted oxidoreductase integral membrane component (CooM/NuoL-like).
 
 
0.891
echB
Ech hydrogenase, subunit B.
 
 
 0.890
RCIX479
[NiFe]-hydrogenase, large subunit (EchE-like).
 
 
 0.855
echE
Ech hydrogenase, subunit E.
  
 
 0.835
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
Server load: low (16%) [HD]