Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RCIX2456Putative transcription factor. (166 aa)    
Predicted Functional Partners:
rpl18e
50S ribosomal protein L18E; Belongs to the eukaryotic ribosomal protein eL18 family.
 
   0.951
pan-2
26s proteasome, regulatory subunit (proteasome-activating nucleotidase); ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, where [...]
 
   0.939
rps3ae
30S ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family.
  
 
 0.914
rps3p
30S ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
 
 
 0.907
rpl29p
50S ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family.
 
 
 0.898
rps17e
30s ribosomal protein S17E; Belongs to the eukaryotic ribosomal protein eS17 family.
 
   0.898
rpl21e
50S ribosomal protein L21E; Belongs to the eukaryotic ribosomal protein eL21 family.
  
   0.892
rps28e
30S ribosomal protein S28E; Belongs to the eukaryotic ribosomal protein eS28 family.
  
   0.887
rpl44e
50S ribosomal protein L44E; Binds to the 23S rRNA.
  
   0.885
tbpE
TATA-box binding protein E; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
  
 
 
 0.885
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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