| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RCIX2456 | pan-2 | RCIX2456 | RCIX2455 | Putative transcription factor. | 26s proteasome, regulatory subunit (proteasome-activating nucleotidase); ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, where [...] | 0.939 |
| RCIX2456 | rpl18e | RCIX2456 | LRC407 | Putative transcription factor. | 50S ribosomal protein L18E; Belongs to the eukaryotic ribosomal protein eL18 family. | 0.951 |
| RCIX2456 | rpl21e | RCIX2456 | RCIX2349 | Putative transcription factor. | 50S ribosomal protein L21E; Belongs to the eukaryotic ribosomal protein eL21 family. | 0.892 |
| RCIX2456 | rpl29p | RCIX2456 | RCIX2549 | Putative transcription factor. | 50S ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family. | 0.898 |
| RCIX2456 | rpl44e | RCIX2456 | LRC297 | Putative transcription factor. | 50S ribosomal protein L44E; Binds to the 23S rRNA. | 0.885 |
| RCIX2456 | rps17e | RCIX2456 | RCIX737 | Putative transcription factor. | 30s ribosomal protein S17E; Belongs to the eukaryotic ribosomal protein eS17 family. | 0.898 |
| RCIX2456 | rps28e | RCIX2456 | LRC144 | Putative transcription factor. | 30S ribosomal protein S28E; Belongs to the eukaryotic ribosomal protein eS28 family. | 0.887 |
| RCIX2456 | rps3ae | RCIX2456 | RCIX2276 | Putative transcription factor. | 30S ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family. | 0.914 |
| RCIX2456 | rps3p | RCIX2456 | RCIX2548 | Putative transcription factor. | 30S ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. | 0.907 |
| RCIX2456 | tbpE | RCIX2456 | RCIX1238 | Putative transcription factor. | TATA-box binding protein E; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. | 0.885 |
| pan-2 | RCIX2456 | RCIX2455 | RCIX2456 | 26s proteasome, regulatory subunit (proteasome-activating nucleotidase); ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, where [...] | Putative transcription factor. | 0.939 |
| pan-2 | rps3ae | RCIX2455 | RCIX2276 | 26s proteasome, regulatory subunit (proteasome-activating nucleotidase); ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, where [...] | 30S ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family. | 0.653 |
| pan-2 | rps3p | RCIX2455 | RCIX2548 | 26s proteasome, regulatory subunit (proteasome-activating nucleotidase); ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, where [...] | 30S ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. | 0.714 |
| pan-2 | tbpE | RCIX2455 | RCIX1238 | 26s proteasome, regulatory subunit (proteasome-activating nucleotidase); ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, where [...] | TATA-box binding protein E; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. | 0.676 |
| rpl18e | RCIX2456 | LRC407 | RCIX2456 | 50S ribosomal protein L18E; Belongs to the eukaryotic ribosomal protein eL18 family. | Putative transcription factor. | 0.951 |
| rpl18e | rpl21e | LRC407 | RCIX2349 | 50S ribosomal protein L18E; Belongs to the eukaryotic ribosomal protein eL18 family. | 50S ribosomal protein L21E; Belongs to the eukaryotic ribosomal protein eL21 family. | 0.998 |
| rpl18e | rpl29p | LRC407 | RCIX2549 | 50S ribosomal protein L18E; Belongs to the eukaryotic ribosomal protein eL18 family. | 50S ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family. | 0.995 |
| rpl18e | rpl44e | LRC407 | LRC297 | 50S ribosomal protein L18E; Belongs to the eukaryotic ribosomal protein eL18 family. | 50S ribosomal protein L44E; Binds to the 23S rRNA. | 0.996 |
| rpl18e | rps17e | LRC407 | RCIX737 | 50S ribosomal protein L18E; Belongs to the eukaryotic ribosomal protein eL18 family. | 30s ribosomal protein S17E; Belongs to the eukaryotic ribosomal protein eS17 family. | 0.995 |
| rpl18e | rps28e | LRC407 | LRC144 | 50S ribosomal protein L18E; Belongs to the eukaryotic ribosomal protein eL18 family. | 30S ribosomal protein S28E; Belongs to the eukaryotic ribosomal protein eS28 family. | 0.993 |