STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dcmC-5 cytosine-specific DNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (419 aa)    
Predicted Functional Partners:
metK
S-adenosylmethionine synthetase.
    
 0.938
ahcY
S-adenosyl-L-homocysteine hydrolase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family.
    
 0.918
mat
Archaeal S-adenosylmethionine synthetase.
     
  0.900
RCIX2532
Predicted endonuclease.
     0.853
RCIX2531
Conserved hypothetical protein.
 
     0.827
RCIX2534
Conserved hypothetical protein.
 
     0.819
RCIX2535
Conserved hypothetical protein.
 
     0.769
dam
N6 adenine-specific DNA-methyltransferase; Identical to orf27 of fosmid clone 3D10mr4.
 
   
 0.668
pcrA
Putative ATP-dependent DNA helicase; Identical to orf21 of fosmid clone 3D10mr4.
  
  
 0.575
RCIX1862
Conserved GTP-binding protein (Ras family).
  
  
 0.553
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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