Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
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[Homology]
Score
RCIX2643Conserved hypothetical protein. (287 aa)    
Predicted Functional Partners:
leuB-2
2-isopropylmalate dehydrogenase.
       0.949
leuD-2
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.
       0.949
leuC-2
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
       0.924
leuA-4
2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
       0.832
RCIX2650
Conserved hypothetical protein.
 
     0.819
RCIX2642
Hypothetical protein.
       0.773
RCIX1549
Conserved hypothetical protein; Similar to orf20 (predicted lipoate synthase) of fosmid clone 1B6mr2.
 
     0.755
RCIX728
Conserved hypothetical protein.
 
     0.739
RCIX2675
Predicted phosphoglycerate mutase.
  
     0.697
RCIX2104
Conserved hypothetical protein.
  
     0.680
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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