| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RCIX2651 | cbiB | RCIX2651 | RCIX2654 | Putative nucleotidyltransferase. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.995 |
| RCIX2651 | cobD | RCIX2651 | RCIX2655 | Putative nucleotidyltransferase. | Putative L-threonine-O-3-phosphate decarboxylase. | 0.916 |
| RCIX2651 | cobQ | RCIX2651 | RCIX2662 | Putative nucleotidyltransferase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.611 |
| RCIX2651 | cobS | RCIX2651 | RCIX2652 | Putative nucleotidyltransferase. | Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.996 |
| cbiB | RCIX2651 | RCIX2654 | RCIX2651 | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Putative nucleotidyltransferase. | 0.995 |
| cbiB | cobD | RCIX2654 | RCIX2655 | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Putative L-threonine-O-3-phosphate decarboxylase. | 0.997 |
| cbiB | cobQ | RCIX2654 | RCIX2662 | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.993 |
| cbiB | cobS | RCIX2654 | RCIX2652 | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.987 |
| cobD | RCIX2651 | RCIX2655 | RCIX2651 | Putative L-threonine-O-3-phosphate decarboxylase. | Putative nucleotidyltransferase. | 0.916 |
| cobD | cbiB | RCIX2655 | RCIX2654 | Putative L-threonine-O-3-phosphate decarboxylase. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.997 |
| cobD | cobQ | RCIX2655 | RCIX2662 | Putative L-threonine-O-3-phosphate decarboxylase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.985 |
| cobD | cobS | RCIX2655 | RCIX2652 | Putative L-threonine-O-3-phosphate decarboxylase. | Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.951 |
| cobD | hisA-2 | RCIX2655 | RRC389 | Putative L-threonine-O-3-phosphate decarboxylase. | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. | 0.874 |
| cobD | hisB | RCIX2655 | RRC390 | Putative L-threonine-O-3-phosphate decarboxylase. | Putative imidazoleglycerol-phosphate dehydratase. | 0.923 |
| cobD | hisD | RCIX2655 | RCIX41 | Putative L-threonine-O-3-phosphate decarboxylase. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.949 |
| cobD | hisE | RCIX2655 | RCIX2673 | Putative L-threonine-O-3-phosphate decarboxylase. | phosphoribosyl-ATP pyrophosphatase. | 0.862 |
| cobD | hisG | RCIX2655 | RCIX583 | Putative L-threonine-O-3-phosphate decarboxylase. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.892 |
| cobD | hisI | RCIX2655 | RCIX21 | Putative L-threonine-O-3-phosphate decarboxylase. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.897 |
| cobQ | RCIX2651 | RCIX2662 | RCIX2651 | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Putative nucleotidyltransferase. | 0.611 |
| cobQ | cbiB | RCIX2662 | RCIX2654 | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.993 |