STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
guaB-2Putative inosine-5'-monophosphate dehydrogenase. (277 aa)    
Predicted Functional Partners:
hisE
phosphoribosyl-ATP pyrophosphatase.
     
 0.824
guaA-2
GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP.
 
  
 0.667
guaA-1
GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP.
 
  
 0.653
smc
Chromosome segregation/partition protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.
 
 
 0.581
RCIX2671
Conserved hypothetical protein.
  
  
 0.565
LRC251
Conserved hypothetical protein.
 
     0.522
RCIX1864
Conserved hypothetical CBS domain protein.
 
     0.516
scpA
Putative chromosome segregation/condensation protein A.
  
  
 0.482
pcn
Putative DNA polymerase sliding clamp (proliferating cell nuclear antigen); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
 
   
 0.457
RCIX1391
Conserved hypothetical protein.
  
     0.445
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.