Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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tgt-2Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (487 aa)    
Predicted Functional Partners:
RCIX415
Putative archaeosine tRNA-ribosyltransferase.
 
     0.948
tgt-1
Archaeosine tRNA-ribosyltransferase.
 
  
0.777
truB
Putative tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
  
  
 0.657
nac
Putative transcription factor (alpha-NAC related); Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
 
     0.633
hisS
histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
  
 0.626
RCIX2622
Conserved GTP-binding protein.
 
  
 0.614
RCIX2687
Hypothetical protein.
     
 0.573
miaB
Putative 2-methylthioadenine synthetase.
  
  
 0.565
nusA
Transcription termination factor NusA; Participates in transcription termination. Belongs to the NusA family.
 
    0.564
RCIX1177
Putative RNA methyltransferase.
  
  
 0.561
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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