Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RCIX269Conserved hypothetical protein. (384 aa)    
Predicted Functional Partners:
RCIX270
Predicted acetylhydrolase.
       0.590
polB-4
DNA-directed DNA polymerase B.
  
    0.504
LRC278
Conserved hypothetical protein.
       0.470
gatB-2
glutamyl-tRNA(Gln) amidotransferase, subunit B; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
 
     0.464
echD
Ech hydrogenase, subunit D.
 
     0.436
RCIX313
Predicted redox-active protein (CxxC motif).
  
   
 0.429
RCIX2074
Hypothetical protein.
  
     0.422
thyA
Putative thymidylate synthase.
  
     0.419
polB-1
DNA-directed DNA polymerase B.
   
    0.404
RCIX870
Putative metallo-phosphoesterase.
 
   
 0.402
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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