Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RCIX2724Putative metallo-beta-lactamase. (272 aa)    
Predicted Functional Partners:
mptE
Conserved hypothetical protein; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family.
    
  0.902
RCIX2725
Conserved hypothetical protein.
 
     0.803
RCIX2726
Conserved hypothetical protein.
       0.601
RCIX1845
Conserved hypothetical protein.
 
     0.532
LRC524
Conserved hypothetical protein; Belongs to the UPF0251 family.
 
     0.512
RCIX2300
Predicted cation efflux protein.
  
    0.490
LRC101
Predicted iron-molybdenum cofactor biosynthesis protein.
 
     0.461
RCIX2401
Conserved hypothetical protein.
 
     0.455
LRC525
Conserved hypothetical protein.
 
     0.448
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
Server load: low (20%) [HD]