Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RCIX287Conserved hypothetical protein; Belongs to the UPF0235 family. (104 aa)    
Predicted Functional Partners:
RCIX285
Conserved hypothetical protein; Belongs to the UPF0292 family.
 
     0.969
trmY
Conserved hypothetical protein; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family.
 
     0.665
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
       0.606
glyS
glycyl-tRNA synthetase.
       0.600
murD
Putative UDP-N-acetylmuramoylalanine-D-glutamate ligase.
 
     0.493
RCIX1837
Conserved hypothetical protein.
  
     0.470
LRC298
Hypothetical protein; Identical to orf9 of fosmid clone 3D10mr4.
 
     0.468
RCIX449
Conserved hypothetical protein.
  
     0.460
mcrD-1
Methyl-coenzyme M reductase, operon protein D.
  
     0.455
RCIX1838
Conserved hypothetical protein.
  
     0.452
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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