Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RCIX325Conserved hypothetical protein. (292 aa)    
Predicted Functional Partners:
nifN
Nitrogenase molybdenum-iron cofactor biosynthesis protein; Belongs to the NifD/NifK/NifE/NifN family.
  
 0.977
nifK
Nitrogenase molybdenum-iron protein, subunit beta (dinitrogenase); Belongs to the NifD/NifK/NifE/NifN family.
  
 0.957
nifD
Nitrogenase molybdenum-iron protein, subunit alpha (dinitrogenase).
 
  
 0.885
nifH-1
Nitrogenase iron protein (nitrogenase reductase); The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
 
  
 0.858
nifH-2
Nitrogenase iron protein (nitrogenase reductase).
 
  
 0.810
nifE
Nitrogenase molybdenum-iron cofactor biosynthesis protein; Belongs to the NifD/NifK/NifE/NifN family.
 
  
 0.789
RCIX35
Conserved hypothetical protein.
 
     0.727
exsB
Succinoglycan biosynthesis regulator; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
 
   
 0.711
queE
Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
     
 0.708
thiL-1
Putative thiamin-monophosphate kinase.
       0.692
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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