Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RCIX377Conserved hypothetical protein. (382 aa)    
Predicted Functional Partners:
RCIX1494
Conserved hypothetical protein.
  
     0.583
RCIX2504
Hypothetical protein.
  
     0.527
hmgA-2
3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
       0.525
RRC166
Putative acetyltransferase (GNAT family).
  
     0.480
LRC452
Hypothetical protein.
  
     0.477
RCIX1518
Predicted oligopeptide transporter (OPT superfamily).
  
     0.461
RRC479
Hypothetical protein.
  
     0.444
RCIX1356
Hypothetical protein.
  
     0.441
RCIX2242
ABC-type transport system, permease component.
  
     0.441
RRC149
Hypothetical protein.
  
     0.439
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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