Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
porD-1Pyruvate:ferredoxin oxidoreductase, delta subunit. (95 aa)    
Predicted Functional Partners:
porC-1
Pyruvate:ferredoxin oxidoreductase, gamma subunit.
 
 0.999
porA-1
Pyruvate:ferredoxin oxidoreductase, alpha subunit.
 
 0.999
porB-1
Pyruvate:ferredoxin oxidoreductase, beta subunit.
 
 0.999
porA-2
Pyruvate:ferredoxin oxidoreductase, alpha subunit.
 
 0.998
porB-2
Pyruvate:ferredoxin oxidoreductase, beta subunit.
 
 0.997
porC-2
Pyruvate:ferredoxin oxidoreductase, gamma subunit.
 
 0.997
cdhE
Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, corrinoid large subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).
  
 
  0.925
cdhD
Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, corrinoid small subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family.
  
 
  0.921
acs-1
acetyl-CoA synthetase (AMP-forming).
   
 
 0.917
acs-2
Putative acetyl-CoA synthetase (AMP-forming).
   
 
 0.917
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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