Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
hypCHydrogenase expression/formation protein (maturation factor). (75 aa)    
Predicted Functional Partners:
hypE
Hydrogenase expression/formation protein (maturation factor).
 
 
 0.996
hypD
Hydrogenase expression/formation protein (maturation factor).
 
 
 0.993
hypA
Hydrogenase expression/formation protein (maturation factor); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.975
hypF
Putative hydrogenase expression/formation protein (maturation factor).
 
 
 0.938
hypB
Hydrogenase expression/formation protein (maturation factor).
 
  
 0.907
vhtG
F420-nonreducing hydrogenase (membrane-bound),small subunit.
 
 
 0.799
vhtA
F420-nonreducing hydrogenase (membrane-bound),large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.781
RCIX1569
Conserved hypothetical protein (HypB/CobW-like).
  
  
 0.685
vhtD
Putative coenzyme F420-nonreducing hydrogenase,subunit D (maturation factor).
 
  
 0.664
nac
Putative transcription factor (alpha-NAC related); Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
       0.590
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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