Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
acyPAcylphosphatase. (88 aa)    
Predicted Functional Partners:
acs-1
acetyl-CoA synthetase (AMP-forming).
     
 0.908
acs-2
Putative acetyl-CoA synthetase (AMP-forming).
     
 0.908
acdB
Acetyl-coa synthetase (ADP-forming), beta subunit.
    
 0.903
acdA
Acetyl-coa synthetase (ADP-forming), alpha subunit.
    
 0.903
acdAB
acetyl-CoA synthetase (ADP-forming), alpha and beta subunit fusion.
    
 0.903
thrS
threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr); Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.786
gap
Glyceraldehyde-3-phosphate dehydrogenase.
     
 0.672
cutA
Divalent cation tolerance protein.
       0.622
RCIX840
Conserved hypothetical protein; Belongs to the UPF0215 family.
       0.622
trpE
Anthranilate synthase, component I.
  
  
 0.434
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
Server load: low (16%) [HD]