Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rnj-2Metallo-beta-lactamase; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily. (445 aa)    
Predicted Functional Partners:
LRC95
Predicted metallo-beta-lactamase.
  
  
 0.927
rnj
Metallo-beta-lactamase; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
  
  
 
0.901
RCIX1254
Putative polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
    0.850
crtE
Putative farnesyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
    0.604
rnz
RNase Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
      
 0.554
rps2p
30S ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family.
 
    0.536
RCIX2365
mRNA cleavage/polyadenylation specificity factor,100 kD subunit.
      
 0.519
rpl37ae
50S ribosomal protein L37AE; Binds to the 23S rRNA.
  
    0.496
secD
Predicted protein secretion system (SecD/SecF family); Involved in protein export.
 
    0.489
rpoA2
DNA-directed RNA polymerase, subunit A2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.482
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
Server load: low (16%) [HD]