Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
RCIX576Predicted signal transduction protein. (992 aa)    
Predicted Functional Partners:
RCIX443
Putative response regulator (CheY-like).
  
 
 0.749
RRC245
Predicted aldo/keto reductase.
    
 0.714
pdhB
Pyruvate dehydrogenase complex E1, transketolase beta subunit.
    
 0.673
dnaK
Chaperonin Hsp70; Acts as a chaperone.
   
 0.668
gap
Glyceraldehyde-3-phosphate dehydrogenase.
  
 
 0.610
hel308
Putative ski2-type helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
   
   0.601
prsA-1
Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family.
  
 0.577
prsA-2
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
  
 0.577
pdhC
Pyruvate dehydrogenase complex E2,dihydrolipoamide acetyltransferase.
    
 0.523
LRC339
Putative signal transduction histidine kinase.
  
   
 0.516
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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