Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RCIX603Conserved hypothetical protein. (252 aa)    
Predicted Functional Partners:
RCIX602
Hypothetical protein.
     
 0.658
fwdC-1
Tungsten formylmethanofuran dehydrogenase,subunit C.
       0.527
fwdA-1
Tungsten formylmethanofuran dehydrogenase,subunit A.
       0.523
fwdB-1
Tungsten formylmethanofuran dehydrogenase,subunit B.
       0.513
nucS
Conserved hypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
  
     0.465
RRC149
Hypothetical protein.
 
  
 0.459
psmB
20S proteasome, beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
  
     0.450
mvhD-1
Coenzyme F420-non-reducing hydrogenase (methyl viologen-reducing hydrogenase), delta subunit.
  
    0.447
fwdD-1
Tungsten formylmethanofuran dehydrogenase,subunit D.
       0.447
hdrA-2
Heterodisulfide reductase, subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
  
    0.437
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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