Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
glnA-1Glutamine synthetase I. (480 aa)    
Predicted Functional Partners:
carA
Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family.
  
 
 0.960
carB
Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family.
  
 0.960
glmS
Glutamine-fructose-6-phosphate amidotransferase,isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.940
gltD
NADPH-dependent glutamate synthase, small subunit.
  
 
 0.939
gdh-1
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.929
gdh-2
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.929
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
 
 0.928
nifH-1
Nitrogenase iron protein (nitrogenase reductase); The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
   
 
 0.928
nifD
Nitrogenase molybdenum-iron protein, subunit alpha (dinitrogenase).
   
 
 0.926
nifK
Nitrogenase molybdenum-iron protein, subunit beta (dinitrogenase); Belongs to the NifD/NifK/NifE/NifN family.
   
 
 0.926
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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