Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cdc48-1Putative cell division cycle protein 48. (942 aa)    
Predicted Functional Partners:
cdc48-3
Cell division cycle protein 48.
  
  
 
0.904
cdc48-2
Cell division cycle protein 48.
  
  
 
0.903
hsp20-2
Chaperonin Hsp20; Belongs to the small heat shock protein (HSP20) family.
 
 
 0.894
RCIX1174
Putative acetoin utilization protein (histone deacetylase superfamily).
 
 
 0.882
rpl40e
50S ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.813
RCIX1976
Signal transduction serine/threonine kinase.
   
 0.782
dnaK
Chaperonin Hsp70; Acts as a chaperone.
  
 0.780
radB
DNA repair/recombination protein B; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.
 
 0.751
RCIX2180
ABC-type transport system, ATPase component.
   
 0.748
psmA
20S proteasome, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
  
 0.733
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.