STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RCIX724Conserved hypothetical protein. (277 aa)    
Predicted Functional Partners:
mcrA
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
 
     0.759
LRC174
Conserved hypothetical protein.
 
     0.755
mcrB
Methyl-coenzyme M reductase, beta subunit.
 
     0.755
LRC169
Conserved hypothetical protein.
  
     0.754
LRC172
Conserved hypothetical protein.
 
     0.752
mcrG
Methyl-coenzyme M reductase, gamma subunit.
 
     0.750
mcrC
Methyl-coenzyme M reductase, operon protein C.
  
     0.747
LRC168
Conserved hypothetical protein.
  
     0.738
LRC527
ABC-type transport system, ATPase component.
  
     0.738
RCIX2003
Conserved hypothetical nitrogenase-related protein.
 
     0.738
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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