close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pycAPutative pyruvate carboxylase, subunit A. (722 aa)    
Predicted Functional Partners:
pycB
Pyruvate carboxylase, subunit B.
 
 
 0.999
birA
biotin--(acetyl-CoA-carboxylase) synthetase.
 
0.991
pyk
Pyruvate kinase (pyruvate phosphotransferase); Identical to orf1 of fosmid clone 3D10mr4; Belongs to the pyruvate kinase family.
  
 
 0.929
pdhA
Pyruvate dehydrogenase complex E1, transketolase alpha subunit.
  
 
 0.928
pdhB
Pyruvate dehydrogenase complex E1, transketolase beta subunit.
    
 0.926
leuA-3
2-isopropylmalate synthase.
  
 
 0.915
porA-1
Pyruvate:ferredoxin oxidoreductase, alpha subunit.
  
 
  0.912
porA-2
Pyruvate:ferredoxin oxidoreductase, alpha subunit.
  
 
  0.912
porC-1
Pyruvate:ferredoxin oxidoreductase, gamma subunit.
    
 0.911
porB-1
Pyruvate:ferredoxin oxidoreductase, beta subunit.
    
 0.911
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
Server load: low (18%) [HD]