| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RCIX1492 | RRC413 | RCIX1492 | RRC413 | OMPdecase domain-containing protein; Conserved hypothetical protein (orotidine 5'-phosphate decarboxylase domain/dimethylmenaquinone methyltransferase domain). | Putative hexulose-6-phosphate isomerase. | 0.997 |
| RCIX1492 | fae-hps | RCIX1492 | RCIX775 | OMPdecase domain-containing protein; Conserved hypothetical protein (orotidine 5'-phosphate decarboxylase domain/dimethylmenaquinone methyltransferase domain). | Formaldehyde activating hexulose-6-phosphate synthase; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily. | 0.933 |
| RCIX1492 | rpi | RCIX1492 | RCIX1835 | OMPdecase domain-containing protein; Conserved hypothetical protein (orotidine 5'-phosphate decarboxylase domain/dimethylmenaquinone methyltransferase domain). | Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.933 |
| RRC413 | RCIX1492 | RRC413 | RCIX1492 | Putative hexulose-6-phosphate isomerase. | OMPdecase domain-containing protein; Conserved hypothetical protein (orotidine 5'-phosphate decarboxylase domain/dimethylmenaquinone methyltransferase domain). | 0.997 |
| RRC413 | fae-hps | RRC413 | RCIX775 | Putative hexulose-6-phosphate isomerase. | Formaldehyde activating hexulose-6-phosphate synthase; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily. | 0.989 |
| cdhC | cdhD | LRC459 | LRC461 | Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family. | Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, corrinoid small subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family. | 0.999 |
| cdhC | fae-hps | LRC459 | RCIX775 | Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family. | Formaldehyde activating hexulose-6-phosphate synthase; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily. | 0.911 |
| cdhC | ftr | LRC459 | LRC202 | Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family. | Formylmethanofuran--tetrahydromethanopterin formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family. | 0.928 |
| cdhC | mtd | LRC459 | RCIX2230 | Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family. | Coenzyme F420-dependent N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT. | 0.406 |
| cdhC | mtrC | LRC459 | RCIX2066 | Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family. | N(5)-methyltetrahydromethanopterin-coenzyme M methyltransferase, subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. | 0.650 |
| cdhC | mtrH | LRC459 | RCIX2071 | Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family. | N(5)-methyltetrahydromethanopterin-coenzyme M methyltransferase, subunit H. | 0.761 |
| cdhD | cdhC | LRC461 | LRC459 | Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, corrinoid small subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family. | Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family. | 0.999 |
| cdhD | fae-hps | LRC461 | RCIX775 | Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, corrinoid small subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family. | Formaldehyde activating hexulose-6-phosphate synthase; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily. | 0.913 |
| cdhD | ftr | LRC461 | LRC202 | Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, corrinoid small subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family. | Formylmethanofuran--tetrahydromethanopterin formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family. | 0.925 |
| cdhD | mtrC | LRC461 | RCIX2066 | Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, corrinoid small subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family. | N(5)-methyltetrahydromethanopterin-coenzyme M methyltransferase, subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. | 0.650 |
| cdhD | mtrH | LRC461 | RCIX2071 | Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, corrinoid small subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family. | N(5)-methyltetrahydromethanopterin-coenzyme M methyltransferase, subunit H. | 0.816 |
| fae-hps | RCIX1492 | RCIX775 | RCIX1492 | Formaldehyde activating hexulose-6-phosphate synthase; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily. | OMPdecase domain-containing protein; Conserved hypothetical protein (orotidine 5'-phosphate decarboxylase domain/dimethylmenaquinone methyltransferase domain). | 0.933 |
| fae-hps | RRC413 | RCIX775 | RRC413 | Formaldehyde activating hexulose-6-phosphate synthase; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily. | Putative hexulose-6-phosphate isomerase. | 0.989 |
| fae-hps | cdhC | RCIX775 | LRC459 | Formaldehyde activating hexulose-6-phosphate synthase; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily. | Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family. | 0.911 |
| fae-hps | cdhD | RCIX775 | LRC461 | Formaldehyde activating hexulose-6-phosphate synthase; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily. | Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, corrinoid small subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family. | 0.913 |