close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vhtAF420-nonreducing hydrogenase (membrane-bound),large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (574 aa)    
Predicted Functional Partners:
vhtG
F420-nonreducing hydrogenase (membrane-bound),small subunit.
 
 
 0.995
hypA
Hydrogenase expression/formation protein (maturation factor); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.915
mvhD-1
Coenzyme F420-non-reducing hydrogenase (methyl viologen-reducing hydrogenase), delta subunit.
  
 
 0.865
mvhD-2
Coenzyme F420-non-reducing hydrogenase (methyl viologen-reducing hydrogenase), delta subunit.
  
 
 0.865
vhtD
Putative coenzyme F420-nonreducing hydrogenase,subunit D (maturation factor).
 
  
 0.864
vhtC
F420-nonreducing hydrogenase (membrane-bound),cytochrome b subunit.
     
 0.848
hypD
Hydrogenase expression/formation protein (maturation factor).
 
 
 0.832
frhD-1
Coenzyme F420-reducing hydrogenase, delta subunit (maturation peptidase).
 
  
 0.830
frhG-2
Coenzyme F420-reducing hydrogenase, gamma subunit.
  
 
 0.826
frhG-1
Coenzyme F420-reducing hydrogenase, gamma subunit.
  
 
 0.826
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.