Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RCIX895Putative metalloprotease (M50 family). (234 aa)    
Predicted Functional Partners:
RCIX450
Putative pheromone shutdown protein (TraB family).
       0.622
rnz
RNase Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
       0.622
RCIX2079
Conserved hypothetical protein.
 
     0.617
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
       0.614
RCIX451
Predicted metalloprotease (M50 family); Belongs to the peptidase M50B family.
 
   
 0.603
RCIX1707
Conserved hypothetical protein.
  
  
 0.511
RCIX894
Putative GTP-binding protein (Ras GTPase family).
       0.510
gpi
Putative glucose-6-phosphate isomerase.
       0.470
adk-1
Putative adenylate kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily.
       0.450
gap
Glyceraldehyde-3-phosphate dehydrogenase.
 
     0.439
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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