STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RCIX927Predicted endonuclease III. (307 aa)    
Predicted Functional Partners:
RRC63
Predicted endonuclease III.
  
  
 
0.913
rnh
Ribonuclease H (RNase H); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
 
  
 0.871
nfo
Putative endonuclease IV.
  
 
 0.846
RCIX2491
Hypothetical protein.
 
 0.824
xthA
Exodeoxyribonuclease III; Gene synonym: exoA.
  
 0.777
RCIX2501
Predicted endonuclease/exonuclease.
  
 0.777
RCIX2726
Conserved hypothetical protein.
    
 
 0.626
cheC
Chemotaxis MCP methylation-inhibitor.
   
   0.592
RCIX2603
Predicted chemotaxis protein (CheW/CheC-like).
   
   0.592
fen
Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...]
  
 
 0.576
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.