STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THAPS_23371Predicted protein. (543 aa)    
Predicted Functional Partners:
TMS1
Possible thymidylate synthase.
  
  
 0.719
APT2
Probable adenine phosphoribosyltransferase.
  
 
 0.709
PNP1
Probable purine-nucleoside phosphorylase.
  
 
 0.698
B8C1B3_THAPS
GMP synthase.
  
  
 0.600
B8BYX4_THAPS
Probable 5'-nucleotidase; Belongs to the 5'-nucleotidase family.
    
 0.587
B8BZC2_THAPS
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
  
 
 0.570
AK2
Adenosine kinase.
   
 
 0.565
PURA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
  
 0.558
B8BWK9_THAPS
PALP domain-containing protein.
   
 
 0.503
B8BZA9_THAPS
Probable amp deaminase.
   
 
 0.496
Your Current Organism:
Thalassiosira pseudonana
NCBI taxonomy Id: 35128
Other names: T. pseudonana
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