STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B8BTG7_THAPSAAA domain-containing protein. (1556 aa)    
Predicted Functional Partners:
B8C8E2_THAPS
UmuC domain-containing protein.
   
 0.963
rfC_2
Replication factor C 37 KD subunit.
   
 0.946
rfC_1
Replication factor C 37 KD subunit.
   
 0.937
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.936
rfC_3
Replication factor C 37 KD subunit.
   
 0.935
rfC2
Replication factor C 36 kDa subunit.
   
 0.934
B8LEH2_THAPS
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
   
 0.907
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.840
B8C3M9_THAPS
RanBP2-type domain-containing protein.
   
 0.818
B8BYS5_THAPS
DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
   
 0.811
Your Current Organism:
Thalassiosira pseudonana
NCBI taxonomy Id: 35128
Other names: T. pseudonana
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