STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B8BTK9_THAPSUroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (392 aa)    
Predicted Functional Partners:
Ppx1
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
 
 
 0.987
Cpx1
Coproporphyrinogen III oxidase, chloroplast targeted.
  
 0.973
B8CE15_THAPS
Uncharacterized protein.
  
 0.971
THAPSDRAFT_719
Uroporphyrinogen_deCOase domain-containing protein.
  
 
 
0.919
UroS
Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
   
 
 0.909
B8BS05_THAPS
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
 
  
 0.828
B8C0R5_THAPS
Glutamyl-tRNA reductase; Belongs to the glutamyl-tRNA reductase family.
  
  
 0.732
PbgD
Porphobilinogen deaminase.
 
 
 0.703
hisH
Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.
   
  
 0.687
THAPSDRAFT_661
Mg-protoporphyrin IX chelatase; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. Belongs to the Mg-chelatase subunits D/I family.
   
  
 0.638
Your Current Organism:
Thalassiosira pseudonana
NCBI taxonomy Id: 35128
Other names: T. pseudonana
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