STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B8BZH3_THAPSTopoisomerase. (650 aa)    
Predicted Functional Partners:
B8CE39_THAPS
Topoisomerase.
 
 
 0.959
B8C807_THAPS
Spo11-like protein.
 
 
 0.937
THAPSDRAFT_105
Eukaryotic translation initiation factor 2 alpha subunit.
   
 
 0.583
RS8
40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family.
 
      0.562
B8CA51_THAPS
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
   
  
 0.554
B8BRG9_THAPS
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
      
 0.543
B8CCN9_THAPS
DNA primase.
      
 0.543
B8CAZ7_THAPS
Uncharacterized protein.
     
 0.542
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
      
 0.499
B8C5H6_THAPS
Uncharacterized protein.
   
  
 0.494
Your Current Organism:
Thalassiosira pseudonana
NCBI taxonomy Id: 35128
Other names: T. pseudonana
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.