STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B8C284_THAPSDeacetylase sirtuin-type domain-containing protein. (211 aa)    
Predicted Functional Partners:
B8LEH2_THAPS
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
  
 
 0.663
B8C1V8_THAPS
Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family.
    
 0.647
H4_2
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.641
THAPS_35693
Sir2-type regulatory transcription factor silent information regulator protein.
  
  
 0.622
B8CAB5_THAPS
Tocopherol polyprenyltransferase-like protein.
    
 0.541
B8C6L3_THAPS
Sir2-like transcriptional regulatory protein found in-like protein.
  
 
0.506
B8C6T1_THAPS
Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
   
 
 0.486
H3-2
Histone H3; Belongs to the histone H3 family.
    
 0.479
H3
Histone H3.
    
 0.479
B8BXC5_THAPS
DUF2236 domain-containing protein.
    
 0.479
Your Current Organism:
Thalassiosira pseudonana
NCBI taxonomy Id: 35128
Other names: T. pseudonana
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.