node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Gura_0002 | Gura_0845 | Gura_0002 | Gura_0845 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: protein of unknown function DUF1568; SMART: Chromosomal replication initiator, DnaA C-terminal domain. | 0.802 |
Gura_0002 | Gura_3098 | Gura_0002 | Gura_3098 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: beta-ketoacyl synthase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR. | 0.654 |
Gura_0002 | recF | Gura_0002 | Gura_0003 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.913 |
Gura_0002 | rnpA | Gura_0002 | Gura_4431 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.570 |
Gura_0845 | Gura_0002 | Gura_0845 | Gura_0002 | PFAM: protein of unknown function DUF1568; SMART: Chromosomal replication initiator, DnaA C-terminal domain. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.802 |
Gura_0845 | Gura_0846 | Gura_0845 | Gura_0846 | PFAM: protein of unknown function DUF1568; SMART: Chromosomal replication initiator, DnaA C-terminal domain. | Retron-type reverse transcriptase-like protein. | 0.636 |
Gura_0845 | Gura_0928 | Gura_0845 | Gura_0928 | PFAM: protein of unknown function DUF1568; SMART: Chromosomal replication initiator, DnaA C-terminal domain. | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.551 |
Gura_0845 | Gura_2887 | Gura_0845 | Gura_2887 | PFAM: protein of unknown function DUF1568; SMART: Chromosomal replication initiator, DnaA C-terminal domain. | PFAM: protein of unknown function DUF1568. | 0.770 |
Gura_0845 | Gura_3098 | Gura_0845 | Gura_3098 | PFAM: protein of unknown function DUF1568; SMART: Chromosomal replication initiator, DnaA C-terminal domain. | PFAM: beta-ketoacyl synthase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR. | 0.471 |
Gura_0845 | Gura_3340 | Gura_0845 | Gura_3340 | PFAM: protein of unknown function DUF1568; SMART: Chromosomal replication initiator, DnaA C-terminal domain. | PFAM: Cobyrinic acid a,c-diamide synthase. | 0.411 |
Gura_0845 | Gura_4256 | Gura_0845 | Gura_4256 | PFAM: protein of unknown function DUF1568; SMART: Chromosomal replication initiator, DnaA C-terminal domain. | Chromosome segregation ATPase; PFAM: Cobyrinic acid a,c-diamide synthase. | 0.411 |
Gura_0845 | gmhA | Gura_0845 | Gura_2864 | PFAM: protein of unknown function DUF1568; SMART: Chromosomal replication initiator, DnaA C-terminal domain. | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | 0.455 |
Gura_0845 | recF | Gura_0845 | Gura_0003 | PFAM: protein of unknown function DUF1568; SMART: Chromosomal replication initiator, DnaA C-terminal domain. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.517 |
Gura_0845 | rnpA | Gura_0845 | Gura_4431 | PFAM: protein of unknown function DUF1568; SMART: Chromosomal replication initiator, DnaA C-terminal domain. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.474 |
Gura_0846 | Gura_0845 | Gura_0846 | Gura_0845 | Retron-type reverse transcriptase-like protein. | PFAM: protein of unknown function DUF1568; SMART: Chromosomal replication initiator, DnaA C-terminal domain. | 0.636 |
Gura_0928 | Gura_0845 | Gura_0928 | Gura_0845 | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | PFAM: protein of unknown function DUF1568; SMART: Chromosomal replication initiator, DnaA C-terminal domain. | 0.551 |
Gura_0928 | rnpA | Gura_0928 | Gura_4431 | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.418 |
Gura_2887 | Gura_0845 | Gura_2887 | Gura_0845 | PFAM: protein of unknown function DUF1568. | PFAM: protein of unknown function DUF1568; SMART: Chromosomal replication initiator, DnaA C-terminal domain. | 0.770 |
Gura_3098 | Gura_0002 | Gura_3098 | Gura_0002 | PFAM: beta-ketoacyl synthase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.654 |
Gura_3098 | Gura_0845 | Gura_3098 | Gura_0845 | PFAM: beta-ketoacyl synthase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR. | PFAM: protein of unknown function DUF1568; SMART: Chromosomal replication initiator, DnaA C-terminal domain. | 0.471 |