STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gura_2390Hypothetical protein. (372 aa)    
Predicted Functional Partners:
Gura_2389
PFAM: iron-containing alcohol dehydrogenase.
       0.693
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.531
Gura_2195
PFAM: Peptidoglycan-binding LysM.
   
    0.529
Gura_3691
PFAM: Peptidoglycan-binding LysM.
   
    0.529
Gura_2508
TIGRFAM: flavoprotein WrbA; PFAM: NADPH-dependent FMN reductase; flavodoxin/nitric oxide synthase.
   
    0.515
Gura_2521
PFAM: NADPH-dependent FMN reductase.
   
    0.515
Gura_3523
PFAM: NADPH-dependent FMN reductase.
   
    0.515
Gura_0727
PFAM: transport-associated protein.
  
    0.505
Gura_2774
Hypothetical protein.
  
     0.494
Gura_3444
Hypothetical protein.
  
     0.483
Your Current Organism:
Geobacter uraniireducens
NCBI taxonomy Id: 351605
Other names: G. uraniireducens Rf4, Geobacter uraniireducens Rf4, Geobacter uraniireducens str. Rf4, Geobacter uraniireducens strain Rf4, Geobacter uraniumreducens JCM 13001
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.