STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Acel_0007Hypothetical protein; KEGG: mbo:Mb0007 possible conserved membrane protein. (152 aa)    
Predicted Functional Partners:
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.789
Acel_0004
PFAM: protein of unknown function DUF721; KEGG: sma:SAV4320 hypothetical protein.
 
     0.733
whiB-2
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.723
Acel_0108
KEGG: fra:Francci3_4418 hypothetical protein.
  
     0.689
Acel_0882
KEGG: tfu:Tfu_1965 hypothetical protein.
  
     0.687
Acel_1553
KEGG: sma:SAV2634 hypothetical protein.
  
     0.679
Acel_1223
Transcriptional regulator, MerR family; SMART: regulatory protein, MerR; KEGG: mpa:MAP1543 hypothetical protein.
  
     0.665
Acel_1404
KEGG: tfu:Tfu_1939 hypothetical protein.
  
     0.661
Acel_2073
KEGG: tfu:Tfu_2746 hypothetical protein.
  
     0.655
Acel_1026
KEGG: tfu:Tfu_1117 hypothetical protein.
  
     0.650
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.