Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Acel_0028PFAM: protein of unknown function DUF75; KEGG: fra:Francci3_1247 protein of unknown function DUF75. (310 aa)    
Predicted Functional Partners:
Acel_1464
PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding; KEGG: sma:SAV7483 hypothetical protein.
   
    0.587
whiB
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.543
nucS
Protein of unknown function DUF91; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
  
     0.517
Acel_0029
PFAM: FAD dependent oxidoreductase; KEGG: sco:SCO1661 putative glycerol-3-phosphate dehydrogenase.
       0.484
whiB-2
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.481
Acel_0004
PFAM: protein of unknown function DUF721; KEGG: sma:SAV4320 hypothetical protein.
  
     0.470
serC
Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
     0.455
Acel_0027
PFAM: Secreted repeat of unknown function; KEGG: sco:SCO7673 lipoprotein.
       0.449
Acel_0347
PFAM: MMPL domain protein; KEGG: fra:Francci3_2666 MmpL.
  
     0.443
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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