Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Acel_0033PFAM: dehydrogenase, E1 component; KEGG: tfu:Tfu_0180 pyruvate dehydrogenase (lipoamide). (372 aa)    
Predicted Functional Partners:
Acel_0032
PFAM: Transketolase, central region; Transketolase domain protein; KEGG: sco:SCO3816 putative branched-chain alpha keto acid dehydrogenase E1 beta subunit.
 0.999
Acel_0031
PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: sco:SCO3815 putative dihydrolipoamide acyltransferase component.
 
 0.996
Acel_0589
Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.995
Acel_1047
PFAM: Transketolase, central region; Transketolase domain protein; KEGG: sso:SSO1526 pyruvate dehydrogenase E1 component, beta subunit.
 0.995
Acel_0936
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; KEGG: sma:SAV6024 putative dihydrolipoamide dehydrogenase.
  
 
 0.946
Acel_0711
KEGG: sco:SCO5523 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV.
   
 
 0.907
Acel_0700
TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: rfr:Rfer_2187 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate.
     
 0.905
Acel_0701
Pyruvate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rfr:Rfer_2186 pyruvate flavodoxin/ferredoxin oxidoreductase-like.
     
 0.905
Acel_0702
Pyruvate ferredoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: rfr:Rfer_2185 thiamine pyrophosphate enzyme-like TPP-binding.
     
 0.905
Acel_1888
L-threonine ammonia-lyase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; amino acid-binding ACT domain protein; KEGG: sco:SCO4962 threonine dehydratase.
     
 0.803
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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