Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mshAGlycosyl transferase, group 1; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. (448 aa)    
Predicted Functional Partners:
Acel_1601
4-alpha-glucanotransferase; KEGG: mbo:Mb1810c probable 4-alpha-glucanotransferase MalQ (amylomaltase) (disproportionating enzyme) (D-enzyme); TIGRFAM: 4-alpha-glucanotransferase; PFAM: glycoside hydrolase, family 77.
 
    
 0.829
mshB
LmbE family protein; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
  
 0.821
mca
LmbE family protein; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
 
  
 0.703
Acel_1829
PFAM: DSBA oxidoreductase; KEGG: nfa:nfa13250 hypothetical protein.
  
     0.664
mshD
GCN5-related N-acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
  
   
 0.587
Acel_0074
Hypothetical protein; KEGG: tfu:Tfu_1879 putative transcriptional regulator.
       0.584
Acel_0448
PFAM: glycosyl transferase, group 1; KEGG: mhu:Mhun_2129 glycosyl transferase, group 1.
  
     0.515
Acel_0072
beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase, family 20; KEGG: sma:SAV5268 putative beta-N-acetylhexosaminidase.
       0.503
Acel_2138
PFAM: Myo-inositol-1-phosphate synthase; Myo-inositol-1-phosphate synthase, GAPDH domain protein; KEGG: tfu:Tfu_3099 myo-inositol-1-phosphate synthase.
     
  0.500
Acel_1772
TIGRFAM: Glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: sco:SCO5187 glutaredoxin-like protein.
  
   
 0.485
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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