Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Acel_0096TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: pae:PA3177 hypothetical protein. (555 aa)    
Predicted Functional Partners:
Acel_1275
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: tte:TTE1717 response regulators consisting of a CheY-like receiver domain and a HTH DNA-binding domain.
  
 0.920
Acel_0529
Diguanylate phosphodiesterase; PFAM: EAL domain protein; KEGG: fra:Francci3_3633 diguanylate phosphodiesterase (EAL domain).
 
    0.829
Acel_0546
PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: sco:SCO5218 integral membrane protein.
 
 
 0.768
Acel_0095
PFAM: beta-lactamase; KEGG: sma:SAV5791 beta-lactamase.
       0.689
Acel_2099
PFAM: EAL domain protein; response regulator receiver; KEGG: tbd:Tbd_1061 putative diguanylate phosphodiesterase (EAL domain) with GAF sensor.
 
  
 0.685
Acel_2100
KEGG: pfl:PFL_3824 sensory box histidine kinase/response regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
 0.656
Acel_1420
TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; KEGG: bja:bll0955 hypothetical protein.
 
0.613
Acel_1595
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: nfa:nfa49640 putative two-component system response regulator.
 
 
    0.516
Acel_1481
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: ana:all0219 hypothetical protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
0.512
Acel_1740
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: mag:amb2277 predicted signal transduction protein containing a membrane domain.
 
   
0.495
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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