Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Acel_0182RNA polymerase, sigma-24 subunit, RpoE; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: sma:SAV909 putative RNA polymerase ECF-subfamily sigma factor. (307 aa)    
Predicted Functional Partners:
Acel_0183
PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; KEGG: sma:SAV908 dehydrogenase.
 
     0.719
Acel_0057
RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: sma:SAV5123 putative RNA polymerase ECF-subfamily sigma factor.
  
  
 0.570
Acel_0481
PFAM: regulatory protein, TetR; KEGG: sma:SAV705 TetR-family transcriptional regulator.
  
     0.522
Acel_0895
PFAM: Carboxymuconolactone decarboxylase; KEGG: rba:RB4395 probable macrophage infectivity potentiator protein Mip.
 
    0.511
Acel_0538
RNA polymerase, sigma subunit, ECF family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: tfu:Tfu_0548 RNA polymerase sigma-70 factor, ECF subfamily.
      
 0.468
Acel_1510
PFAM: NAD-dependent epimerase/dehydratase; KEGG: nfa:nfa16530 hypothetical protein.
 
     0.442
Acel_1134
Transcriptional regulator; KEGG: tfu:Tfu_1988 putative DNA-binding protein.
  
    0.436
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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