Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Acel_0225PFAM: protein of unknown function DUF1222; KEGG: mpa:MAP3685c hypothetical protein. (485 aa)    
Predicted Functional Partners:
Acel_0226
KEGG: sma:SAV4712 hypothetical protein.
       0.757
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
      0.672
Acel_0496
KEGG: sco:SCO4689 hypothetical protein.
  
     0.631
Acel_0224
PFAM: CheW domain protein; KEGG: pca:Pcar_1198 CheW protein.
       0.554
Acel_0025
PFAM: Kelch repeat-containing protein; KEGG: xla:446327 influenza virus NS1A binding protein Pfam: BTB Herpes_UL33 BACK Kelch_1 Kelch_2 PROSITE: BTB.
  
     0.425
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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