STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
disAProtein of unknown function DUF147; Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions. (368 aa)    
Predicted Functional Partners:
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
  
  
 0.949
Acel_0230
PFAM: aminotransferase class-III; KEGG: sco:SCO6769 probable aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
       0.773
Acel_0155
KEGG: fra:Francci3_0065 hypothetical protein.
  
     0.741
Acel_0391
PFAM: 2',5' RNA ligase; KEGG: fra:Francci3_0662 2',5' RNA ligase.
  
     0.618
Acel_1775
PFAM: UvrD/REP helicase; KEGG: tfu:Tfu_0524 putative DNA helicase; Belongs to the helicase family. UvrD subfamily.
   
    0.588
Acel_1776
PFAM: UvrD/REP helicase; SMART: AAA ATPase; KEGG: tfu:Tfu_0523 putative ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily.
   
    0.588
Acel_0772
TIGRFAM: degV family protein; PFAM: DegV family protein; KEGG: sco:SCO2569 hypothetical protein.
  
    0.413
Acel_0080
PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; KEGG: fra:Francci3_4254 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase.
  
    0.411
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.