STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLTIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class-III; KEGG: sma:SAV4795 putative glutamate-1-semialdehyde 2,1-aminotransferase. (437 aa)    
Predicted Functional Partners:
Acel_0235
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: tfu:Tfu_2730 porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.996
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.993
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.975
Acel_0236
uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sma:SAV4741 uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase.
 
  
 0.875
Acel_1616
TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: tfu:Tfu_2221 uroporphyrin-III C-methyltransferase, C-terminal:siroheme synthase, N-terminal.
 
   
 0.831
Acel_0250
PFAM: Phosphoglycerate mutase; KEGG: nfa:nfa51590 hypothetical protein.
  
    0.807
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.715
Acel_0252
PFAM: cytochrome c biogenesis protein, transmembrane region; KEGG: tfu:Tfu_2703 putative cytochrome c biogenesis membrane protein.
  
  
 0.649
Acel_0232
PFAM: phosphoesterase; KEGG: sma:SAV5971 secreted acid phosphatase.
       0.628
Acel_1199
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
    
 0.625
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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