Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Acel_0249PFAM: Xylose isomerase domain protein TIM barrel; KEGG: fra:Francci3_0473 xylose isomerase-like. (265 aa)    
Predicted Functional Partners:
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
       0.638
Acel_0248
PFAM: Proline dehydrogenase; KEGG: tfu:Tfu_0434 proline dehydrogenase.
       0.638
Acel_0246
PFAM: histone deacetylase superfamily; KEGG: tfu:Tfu_2707 putative acetoin utilization protein.
 
     0.637
Acel_0253
PFAM: ResB family protein; KEGG: tfu:Tfu_2702 putative integral membrane protein.
 
     0.631
Acel_0245
KEGG: sma:SAV5282 hypothetical protein.
 
    0.602
Acel_0250
PFAM: Phosphoglycerate mutase; KEGG: nfa:nfa51590 hypothetical protein.
       0.564
Acel_0539
KEGG: tfu:Tfu_0549 anti-sigma factor.
  
     0.533
Acel_0693
PFAM: Methionine synthase, vitamin-B12 independent; KEGG: tfu:Tfu_0602 hypothetical protein.
  
     0.513
whiB-3
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.501
Acel_0218
KEGG: fra:Francci3_3498 putative Lsr2-like protein.
  
     0.490
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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