STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Acel_0365PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: sma:SAV4998 two-component system response regulator. (199 aa)    
Predicted Functional Partners:
Acel_0516
Putative signal transduction histidine kinase; PFAM: GAF domain protein; ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region; KEGG: sco:SCO3948 two component sensor.
 
 
 0.899
Acel_0974
Putative signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region; KEGG: sth:STH650 two-component system sensor kinase.
 
 
 0.875
Acel_1387
Periplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; KEGG: mag:amb3665 signal transduction histidine kinase.
 
   0.861
Acel_0194
Putative signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region; KEGG: sco:SCO5131 two-component system sensor kinase.
 
 
 0.855
Acel_0262
PFAM: response regulator receiver; KEGG: fra:Francci3_0524 response regulator receiver protein.
  
     0.736
Acel_2100
KEGG: pfl:PFL_3824 sensory box histidine kinase/response regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
  
 
 0.514
Acel_0165
Diguanylate cyclase with GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; histidine kinase, HAMP region domain protein; KEGG: ade:Adeh_2704 diguanylate cyclase (GGDEF domain).
  
 
 0.467
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.453
Acel_0364
KEGG: nfa:nfa8910 hypothetical protein.
       0.446
Acel_0367
TIGRFAM: IMP dehydrogenase family protein; KEGG: tfu:Tfu_2595 IMP dehydrogenase related 2.
     
 0.439
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.