Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Acel_0376PFAM: peptidase M23B; KEGG: tte:TTE2691 membrane proteins related to metalloendopeptidase. (271 aa)    
Predicted Functional Partners:
Acel_0377
TIGRFAM: Methylmalonyl-CoA mutase-like; PFAM: cobalamin B12-binding domain protein; KEGG: ade:Adeh_1832 methylmalonyl-CoA mutase.
       0.552
Acel_1845
KEGG: sco:SCO5138 hypothetical protein.
    
 0.551
Acel_2150
PFAM: Peptidoglycan-binding domain 1 protein; cell wall hydrolase/autolysin; KEGG: fra:Francci3_4538 cell wall hydrolase/autolysin.
 
  
 0.493
mltG
Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
  
   
 0.457
Acel_2004
PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase; PASTA domain containing protein; KEGG: tfu:Tfu_0109 PASTA.
  
   
 0.431
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
 
 
 0.412
Acel_1729
C-terminal processing peptidase-3; KEGG: sma:SAV5106 putative carboxy-terminal processing protease precursor; TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41; Serine peptidase; MEROPS family S41A; Belongs to the peptidase S41A family.
 
 
 
 0.407
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
 
   
 0.403
Acel_1730
Cell division protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
  
 0.401
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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