Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
Score
Acel_0432KEGG: gka:GK1960 hypothetical protein. (306 aa)    
Predicted Functional Partners:
Acel_0433
Dihydroxyacid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: ret:RHE_PC00044 dihydroxy-acid dehydratase protein; Belongs to the IlvD/Edd family.
       0.773
Acel_0434
Carbohydrate ABC transporter substrate-binding protein, CUT1 family; PFAM: extracellular solute-binding protein, family 1; KEGG: sco:SCO2231 putative maltose-binding protein; TC 3.A.1.1.-.
       0.757
Acel_1827
PFAM: O-methyltransferase, family 3; Methyltransferase type 11; KEGG: fra:Francci3_3834 O-methyltransferase, family 3.
  
  
 0.661
nuoI
NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
   0.646
Acel_0431
KEGG: bha:BH0491 hypothetical protein.
     
 0.623
Acel_0273
NADH dehydrogenase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.
   
   0.610
Acel_0271
TIGRFAM: NADH-quinone oxidoreductase, E subunit; PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit; KEGG: sco:SCO4566 NADH dehydrogenase I chain E.
    
   0.602
Acel_0272
NADH dehydrogenase subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
    
   0.602
Acel_0435
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: oih:OB0775 sugar ABC transporter permease; TC 3.A.1.1.-.
       0.559
dop
Protein of unknown function DUF245 domain protein; Displays depupylase (DPUP) activity, removing conjugated Pup from target proteins; is thus involved in the recycling of Pup and may function similarly to deubiquitinases (DUBs) in eukaryotes to prevent or promote proteasomal degradation of certain proteins. Is also able to catalyze the deamidation of the C-terminal glutamine to glutamate in a variant of the prokaryotic ubiquitin-like protein Pup; however, since Pup from A.cellulolyticus possesses a C-terminal glutamate, this deamidase activity may be of no significance in vivo.
  
  
 0.535
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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