STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Acel_0539KEGG: tfu:Tfu_0549 anti-sigma factor. (90 aa)    
Predicted Functional Partners:
Acel_0538
RNA polymerase, sigma subunit, ECF family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: tfu:Tfu_0548 RNA polymerase sigma-70 factor, ECF subfamily.
  
 
 0.973
Acel_0201
KEGG: sma:SAV4663 hypothetical protein.
 
    0.761
Acel_1521
PFAM: GCN5-related N-acetyltransferase; KEGG: fra:Francci3_3572 GCN5-related N-acetyltransferase.
  
     0.586
Acel_0882
KEGG: tfu:Tfu_1965 hypothetical protein.
  
     0.561
Acel_0249
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: fra:Francci3_0473 xylose isomerase-like.
  
     0.533
Acel_0693
PFAM: Methionine synthase, vitamin-B12 independent; KEGG: tfu:Tfu_0602 hypothetical protein.
  
     0.530
Acel_1777
PFAM: UBA/THIF-type NAD/FAD binding protein; Rhodanese domain protein; MoeZ/MoeB domain protein; KEGG: sco:SCO5178 putative sulfurylase.
   
    0.512
mca
LmbE family protein; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
  
   
 0.497
Acel_2134
KEGG: sma:SAV4293 transmembrane protein.
  
     0.491
Acel_1776
PFAM: UvrD/REP helicase; SMART: AAA ATPase; KEGG: tfu:Tfu_0523 putative ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily.
  
     0.460
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.