STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Acel_0564RNA polymerase, sigma 28 subunit, SigD/FliA/WhiG; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: fra:Francci3_3755 sigma 28 subunit; Belongs to the sigma-70 factor family. (287 aa)    
Predicted Functional Partners:
Acel_0565
Putative anti-sigma regulatory factor, serine/threonine protein kinase; KEGG: sco:SCO5244 anti-sigma factor.
 
 
 0.980
Acel_0065
KEGG: sma:SAV4026 AmfC protein.
    
 
 0.786
Acel_0561
PFAM: diacylglycerol kinase, catalytic region; KEGG: sco:SCO5241 hypothetical protein.
       0.773
Acel_0562
Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain-like protein; KEGG: gka:GK1441 hypothetical protein.
       0.773
Acel_0563
Hypothetical protein.
       0.773
Acel_1873
CheA signal transduction histidine kinase; PFAM: response regulator receiver; CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Hpt domain protein; KEGG: ade:Adeh_0613 CheA signal transduction histidine kinase.
  
  
 0.728
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.724
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.720
Acel_1975
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: fra:Francci3_4302 anti-sigma-factor antagonist (STAS) domain protein.
 
 
 0.716
Acel_0839
PFAM: protein of unknown function DUF1078 domain protein; KEGG: lxx:Lxx06310 flagellar basal-body rod protein.
  
 
 0.711
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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