Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Acel_0593PFAM: Allophanate hydrolase subunit 1; KEGG: fra:Francci3_2974 allophanate hydrolase subunit 1. (234 aa)    
Predicted Functional Partners:
Acel_0594
KEGG: sma:SAV6937 antagonist of KipI; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2.
 
 0.999
pxpA
LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
  
 0.998
Acel_0548
PFAM: phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: gka:GK1599 acetyl-CoA carboxylase.
 
   0.739
Acel_0430
PFAM: regulatory proteins, IclR; KEGG: mta:Moth_0417 transcriptional regulator, IclR family.
  
    0.619
Acel_1592
Transcriptional regulator, IclR family; PFAM: regulatory proteins, IclR; KEGG: tfu:Tfu_0625 regulatory proteins, IclR.
  
    0.619
Acel_0596
PFAM: natural resistance-associated macrophage protein; KEGG: mpa:MAP2066 hypothetical protein.
  
  
 0.524
Acel_1975
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: fra:Francci3_4302 anti-sigma-factor antagonist (STAS) domain protein.
   
    0.511
Acel_0591
Putative signal-transduction protein with CBS domains; PFAM: CBS domain containing protein; KEGG: mta:Moth_1851 CBS domain containing membrane protein.
       0.401
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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